1. Changes in Urination

One of the earliest signs of kidney disease is changes in urine production. You may notice increased frequency of urination, especially during the night. On the other hand, you may experience decreased urination or foamy urine.
2. Fatigue and Weakness

Kidney disease can lead to anemia, a condition characterized by low red blood cell count. This can result in persistent fatigue, weakness, and difficulty concentrating.
3. Swelling

Excessive fluid buildup in the body, known as edema, commonly occurs with kidney disease. Swelling can affect the legs, hands, face, and even the abdomen.
4. Persistent Back Pain

Kidney disease can cause back pain, usually felt just below the ribcage. The pain may be severe and persistent, often accompanied by tenderness. This will often accompany a urinary tract infection that has gone untreated.