Preheat your oven to 350°F (175°C).
Pat the pork loin roast dry with paper towels and season it generously with salt and pepper.
In a small bowl, mix together the barbecue sauce, brown sugar, Dijon mustard, garlic powder, and onion powder.
Heating a large skillet over medium-high heat, add the olive oil. Once hot, sear the pork loin for about 2-3 minutes on each side until it’s nicely browned.
Transfer the seared pork loin onto a baking dish and brush it generously with the barbecue sauce mixture, reserving some for later.
Place in the oven and roast for about 40-50 minutes or until the internal temperature reaches 145°F (63°C), basting it occasionally with the reserved barbecue glaze.
Let the roast rest for about 10 minutes before slicing it into thick pieces.
Serve the slices drizzled with any remaining glaze.
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Variations & Tips
If you’re feeling adventurous, try mixing your favorite hot sauce into the glaze for a spicier kick. Alternatively, you can experiment with different mustard types, like spicy brown or whole grain, to add more depth to the flavor. For a more smoky profile, add a teaspoon of smoked paprika to the glaze. A slow cooker version can be made by setting the pork loin in the cooker with the glaze and cooking on low for about 6-8 hours until tender.
