Combine meat, salt, pepper, onion powder, and garlic powder in a medium bowl.
Form into 4 patties, about 1/2″ thick. Make a small indent in the middle of the patty with your thumb. Brush patties with barbecue sauce if using.
Preheat the air fryer to 370°F. Add patties in a single layer to the basket.
Cook 6 minutes. Flip burger over and cook an additional 3-5 minutes or until beef reaches 160°F.
Add cheese if using and cook 1 minute more.
Enjoy 🤤😋
