Scientific discovery that turns mouse skin transparent echoes plot of H.G. Wells’ ‘The Invisible Man’ (Page 2 ) | September 7, 2024
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In H.G. Wells’ 1897 science fiction novel, “The Invisible Man,” the protagonist invents a serum that makes the cells in his body transparent by controlling how they bend light.

More than 100 years later, scientists have discovered a real-life version of the substance: A commonly used food coloring can make the skin of a mouse temporarily transparent, allowing scientists to see its organs function, according to a new study published Thursday in the journal Science.

The breakthrough could revolutionize biomedical research and, should it be successfully tested in humans, have wide-ranging applications in medicine and health care, such as making veins more visible to draw blood.

Researchers made the skin on the skulls and bellies of live mice transparent by applying a mixture of water and a yellow food coloring called tartrazine. Washing away any remaining solution reversed the process, which did not harm the animals. The mice’s fur was removed before the application of the solution.

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