Severe Constipation and Toxic Megacolon: Causes and Solutions (Page 2 ) | May 15, 2025

Sedentary lifestyle

Overuse of laxatives

Opioid or antidepressant medications

Neurological disorders (e.g., Parkinson’s, MS)

Colorectal obstruction (tumors, strictures)

⚠️ Toxic Megacolon Causes:
Inflammatory bowel disease (IBD) – especially ulcerative colitis

Infections – particularly Clostridium difficile (C. diff)

Ischemic colitis (restricted blood flow)

Colonic pseudo-obstruction

Chagas disease (in some parts of Latin America)

Symptoms to Watch For
🟡 Severe Constipation:
No bowel movement for several days

Abdominal pain or bloating

Hard, dry stools

Nausea or loss of appetite

Straining or incomplete evacuation

🔴 Toxic Megacolon (Medical Emergency):
Sudden, severe abdominal pain

Swollen, tender belly

Fever and chills

Rapid heart rate

Dehydration

Confusion or weakness

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