Kidney and liver markers also mattered. High creatinine and elevated liver enzymes were tied to lower odds of exceptional longevity, suggesting that long-term organ strain may influence lifespan.
Uric acid showed a strong trend as well: the lowest levels were associated with higher chances of reaching 100. Because uric acid relates to inflammation, this may hint at lower chronic inflammatory burden in long-lived individuals.
Overall, the study suggests that extremes—very high or very low lab values—tend to reduce the odds of reaching 100. While no test predicts an individual’s future, these patterns highlight the value of balanced metabolic and organ health over time.
