Warning! 8 Medications That Cause Severe Dementia (Page 3 ) | November 18, 2025

Amphetamines are used to treat attention deficit hyperactivity disorder (ADHD). Although they temporarily improve concentration, prolonged use can lead to memory loss and other lasting cognitive impairment. They are physically and emotionally addictive and can cause serious problems such as heart arrhythmias.

It is essential that healthcare professionals carefully monitor their prescriptions. Non-pharmacological approaches such as behavioral therapy should also be considered.

First-generation antihistamines: Relief today, problem tomorrow.
First-generation antihistamines, such as diphenhydramine, are used to treat allergies, but they can cause cognitive impairment due to their anticholinergic effects. A recent study showed that their prolonged use is associated with an increased risk of dementia.

Less harmful alternatives, such as cetirizine, are preferred for the long-term treatment of allergies. It is important to consult a doctor before taking these medications for an extended period.

Tricyclic antidepressants and memory loss:
Tricyclic antidepressants, such as amitriptyline, increase the availability of several neurotransmitters, but they also have anticholinergic effects. This links them to a higher risk of dementia and cognitive decline, especially in older adults.

Currently, there are safer alternatives, such as selective serotonin reuptake inhibitors (SSRIs), which offer a better safety profile.

Statins and cognitive function

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